Altis Biosystems

Altis Biosystems is a Durham, North Carolina-based biotechnology company specializing in innovative in vitro models for pre-clinical drug discovery.

We support life science researchers by providing expertise and unique RepliGut® Systems, a collection of in vitro models derived from stem cells, designed to accurately replicate human intestinal physiology.

Altis Biosystems’ RepliGut® models overcome the limitations of conventional cell lines and animal models, offering a highly accurate and scalable platform for studying drug disposition, toxicity, and efficacy – ultimately reducing the reliance on animal testing and accelerating the drug development process. Our RepliGut® Planar models, in particular, advance novel pharmaceuticals by harnessing the potential of human donor intestinal stem cells.

We offer a range of services including InflammaScreen, StemTox, and custom assays, alongside our core RepliGut® Kits, enabling researchers to gain valuable insights into human gut biology. Altis Biosystems is committed to advancing New Approach Methodologies (NAMs) for a safer and more effective future in drug development.