SPYRYX Biosciences
Durham, United States (US) · Health and Medical
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Last verified
May 2026
Overview
SPYRYX Biosciences is a Durham, North Carolina-based biopharmaceutical company dedicated to developing innovative inhaled therapeutics for severe respiratory diseases, with Cystic Fibrosis (CF) as its initial target.
We focus on addressing the underlying mechanisms of lung disease, particularly the dehydration associated with conditions like CF, by utilizing novel peptides that reduce airway surface density of epithelial sodium channels (ENaC).
Our lead program, SPX-101, is currently in a Phase 2 clinical trial, entitled "Hydration for Optimal Pulmonary Effectiveness" (HOPE-1), evaluating the efficacy of our approach in individuals living with CF. Spyryx Biosciences is committed to advancing understanding of airway hydration and respiratory biology through rigorous scientific research and development.
We are a team of dedicated scientists and clinicians driven by a passion for improving the lives of patients suffering from respiratory illnesses.
We focus on addressing the underlying mechanisms of lung disease, particularly the dehydration associated with conditions like CF, by utilizing novel peptides that reduce airway surface density of epithelial sodium channels (ENaC).
Our lead program, SPX-101, is currently in a Phase 2 clinical trial, entitled "Hydration for Optimal Pulmonary Effectiveness" (HOPE-1), evaluating the efficacy of our approach in individuals living with CF. Spyryx Biosciences is committed to advancing understanding of airway hydration and respiratory biology through rigorous scientific research and development.
We are a team of dedicated scientists and clinicians driven by a passion for improving the lives of patients suffering from respiratory illnesses.
Contact Details
info@spyryxbio.com
Durham, United States (US), 801-10 Capitola Drive
Founded
2013
Company Type
Private Limited Company
Employees
10-20
Categories
Keywords
#respiratory therapeutics
#cystic fibrosis
#pulmonary
#rare and orphan diseases
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