Target RWE

Pedestal Health and Headwater Science are now two distinct companies under Highlander Health, dedicated to revolutionizing evidence generation for life sciences and health systems.

Pedestal Health, formerly Target RWE, is a full-service evidence generation partner, delivering scientifically rigorous, regulatory-ready longitudinal datasets. We specialize in liver disease, dermatology, and gastroenterology, providing insights that improve patient care through continuous evidence.

Headwater Science, formerly NoviSci, is a methodological and analytical engine focused on real-world data. We develop advanced study designs, analytic frameworks, and infrastructure, supporting sponsors, regulators, and the peer-reviewed literature with causal inference and data analytics.

Together, these companies form the core of Highlander Health’s vision: to reduce treatment access time by 50% through continuous evidence generation and more personalized care. Founded by Amy Abernethy, M.D., Ph.D., and Brad Hirsch, M.D., Highlander Health is committed to modernizing episodic research with an infrastructure that compounds over time.