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Upstream Biotechnology

Durham, United States (US) · Health and Medical

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Data quality

Complete · Accuracy

Last verified

May 2026

Overview

Upstream Biotechnology is a Durham, North Carolina-based biotechnology company dedicated to engineering crop resilience for a sustainable food future.

With the global population projected to reach 10 billion by 2050, Upstream Biotechnology addresses the urgent need for increased agricultural productivity in the face of climate change and evolving food security challenges.

Our patented SwitchBlade Technology utilizes natural RNA-based solutions to modulate plant immunity, providing broad-spectrum resistance against diseases and abiotic stresses – all without compromising yield. We are focused on partnering with seed companies to deliver next-generation traits that enhance grower profitability and build resilience across the value chain.

Upstream Biotechnology is currently developing a pipeline of traits for key crops, including soy, and actively seeking collaborations for field trials and commercialization.

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Contact Details

contact@upstreambiotech.com

Durham, United States (US), 701 West Main Street

Founded

2018

Company Type

Private Limited Company

Employees

2-10

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