20 revolutionary neuroscience startups to know in 2023

September 06, 2023

Revolutionary neuroscience startups enhancing the industry with amazing innovations

As neuroscience is becoming a more mainstream-friendly subject, neuroscience startups are working hard to bring solutions that utilize this modern scientific field to help people improve their lives.

The Neuroscience market size was worth around US$ 31.80 billion in 2021 and is estimated to hit approximately US$ 39.09 billion by 2028.


What are neuroscience startups?

Neuroscience startups are working on solutions that help us understand mental conditions and they advance the detection, prognosis, and treatment of patients affected by neurological and neuropsychiatric disorders.

Flow Neuroscience

Founded in 2018, Flow Neuroscience creates non-invasive headsets that target key brain areas involved in mood regulation using transcranial direct current stimulation (tDCS). Their solutions aim to relieve depression symptoms.

Flow Neuroscience’s products enable research-backed brain stimulation treatments conveniently at home as part of an affordable subscription plan. Their goal is providing drug-free depression relief and tools for emotional wellbeing.

Verge Genomics

Founded in 2015, Verge Genomics developed an AI platform that analyzes massive biological datasets to identify promising new drug compounds that could prevent progression of neurodegeneration. This aims to make the discovery process faster and more focused.

Verge Genomics uses computational approaches to uncover novel therapeutic targets and viable lead treatments for hitherto untreatable nervous system diseases. Their AI solutions enhance R&D capabilities.


Founded in 2015, BrainCo creates wearable neuroheadsets that use AI to decode brain activity, provide neurofeedback, and control prosthetics intuitively. Their tools target focus, relaxation, rehabilitation, and more through patented brain training techniques.

By making therapeutic neurotechnology accessible, BrainCo aims to enhance cognitive capabilities and overall wellbeing. Their innovations blend ancient wisdom around mental states with modern biofeedback.


Founded in 2011, Brain.fm has developed generative soundscapes tuned to put the brain into flow states optimized for activities like studying, working, or unwinding. Users can select tracks to match desired mental states.

Brain.fm aims to harness the brain’s neuroplasticity through engineered sound environments that entrain neural oscillations. Their technology leverages music’s effects on cognition and mood.


Founded in 2016, Neuralink has engineered a fully implanted wireless BCI system called Link which uses tiny flexible electrode threads to interact with neurons. Their platform aims to enable thoughts, emotions, and actions to be transmitted seamlessly.

Potential applications include restoring motor function, treating neurological conditions, and merging artificial and human intelligence. Neuralink’s neurotechnology promises a future where disabilities are remedied and human potential is expanded.


Founded in 2017, Motorica engineers prosthetic arms and hands that integrate sensors to decode muscle signals from an amputee’s residual limb. This biofeedback enables intuitive prosthetic movements and grip strength modulation.

By closing the loop between intent and action, Motorica aims to revolutionize prosthetics with bionic limbs that emulate natural feel and dexterity for improved quality of life. Their advances help amputees seamlessly regain abilities.

Cala Health

Founded in 2015, Cala Health produces non-invasive devices that target the peripheral nervous system using electrical nerve stimulation to treat hand tremors, chronic pain, and more. The therapies aim to replace pharmaceuticals.

Cala’s wrist-worn stimulator called Cala Trio can override nerve signals causing involuntary muscle contractions to control essential tremor with personalized neurostimulation algorithms. Further target indications are in their pipeline.


Founded in 2020, Arctop enables any enterprise to incorporate neuromarketing technology once only accessible to research firms. Their self-serve platform democratizes brain data to inform business and product design. Initial target customers include gaming and edtech companies.

Backed by investors like Google Ventures, Arctop is scaling scientific brain decoding for mainstream applications. Their solution leads commercial neuromonitoring into an ethical new era focused on elevating end-user experiences versus manipulation.


Founded in 2012 by former NASA scientists, Neurotrack realized advanced perceptual analytics could transform imprecise subjective dementia diagnoses burdening patients and clinicians. Their evidence-based tools lead the quest for greater brain health vigilance.

With clinical trials validating capability to detect pre-symptomatic Alzheimer’s, Neurotrack is partnering with providers, Medicare networks and pharma to make state-of-the-art pre-screening widely accessible. Early cognitive intervention is now possible.


Founded in 2018, Hippoc taps advancements in computer vision, neuroscience, and machine learning to bring quantifiable behavioral data to what was traditionally subjective creative work. Their analytics approach lifts performance ceilings for brands and designers.

Early adopters spanning major consumer brands, ad agencies, and platform partners validate demand for media effectiveness measured by actual human responses versus proxies like clicks or surveys. Hippoc leads design into a new data-centered era.

HRL Laboratories

Founded in 1948 by aerospace pioneer Howard Hughes, HRL has partnered with Boeing and GM since 2004 to stay on the leading edge of physical science, continuing Hughes’ mission to “organize scientific research for the benefit of mankind.

Major past inventions include chemical gas lasers, atomic clocks, night vision systems and advanced sensors. Ongoing research spans materials, energy, neurotech, microchip fabrication, AI and more. Their discoveries build the technological edge of their parent companies.


Founded by a stroke survivor, Neurofenix aims to drive breakthroughs in post-stroke therapy using innovations once confined to elite research labs. Their solution combines clinical rigor with engineering excellence to maximize patient outcomes through cutting-edge neurotech.

With continued refinements towards commercialization, the Neurofenix system heralds a new generation of rehabilitation where technology doesn’t just assist recovery but accelerates it by optimally engaging neuroplasticity. Their breakthroughs restore real hope for the future.

Braingineers International

Founded in 2020 by neuroscience pioneers, CoMind tackles the hard problem of seamlessly interfacing with the brain without implants. Their breakthroughs in high-density sensing and machine learning push non-invasive technology closer to the capabilities of implanted BCIs.

CoMind aims to first enable new independence for patients through their research-grade platform, then bring their innovations to mass-market devices enabling brain-based interactions. Investors include Andreessen Horowitz and Meta.


Founded in 2018, Braingineers realized that traditional methods failed to capture users’ complete emotional journey. Their biometrics analysis provides unprecedented visibility into how humans react at a neurological level to drive better experiences.

Early clients spanning major consumer brands to ad agencies validate the competitive advantage gained from optimizing based on customers’ true biological responses rather than superficial proxies. Braingineers leads experience design into the future.


Founded in 2018 by pioneering Harvard Medical School scientists, Imaginostics builds on decades of cross-disciplinary MRI research to commercialize imaging breakthroughs only recently made possible by computational power. Their biomarkers quantify disease in ways previously unattainable.

Backed by GE Healthcare and AI chipmaker Kneron, Imaginostics pairs clinical expertise with engineering excellence to drive a new era of diagnostic and predictive imaging. Their innovations unlock an untapped wealth of biomedical intelligence contained within routine scans.

Alpha Fiber

Founded in 2021, Alpha Fiber utilizes computer vision algorithms to analyze video footage of collisions and impacts. Their AI assesses head motion to identify suspected concussions requiring examination.

By providing real-time detection, Alpha Fiber aims to improve concussion screening across youth, school, and professional sports. Their unobtrusive system promises more comprehensive monitoring during games and practices.

Brainovative Labs

Founded in 2016, Brainovative Labs develops hardware and software to help people with disabilities communicate and interact with technologies more easily. Their products aim to increase engagement and independence.

Current offerings include speech generation devices, switch interfaces, and eye gaze technologies. By creatively applying technology, Brainovative enables simpler navigation of smartphones, computers, and more based on each user’s abilities.

Connecta Therapeutics

Founded in 2020, Connecta Therapeutics discovers and advances promising drug candidates targeting CNS conditions with limited therapies. Their pipeline focuses on disorders like chronic pain, addiction, and epilepsy.

By applying new scientific insights around neural pathways, Connecta aims to translate emerging biology into transformative medicines that improve treatment outcomes.


Founded in 2020, Axorus designs implantable devices that record from and stimulate the nervous system. Their electrodes aim to treat conditions like paralysis, arthritis, and immune disorders.

By creating a channel for bidirectional communication with nerves, Axorus’ implants hold potential to restore lost function and modulate disease signals. Their disruptive approach promises new options for unmet needs.


Founded in 2020, emoty.AI applies computer vision and machine learning to analyze facial expressions and emotional responses in video. Their AI quantifies sentiment, engagement, and reactions.

By automating emotion analytics, emoty.AI aims to help companies extract insights from customer behavior effortlessly. The data promises to aid creative development, design iteration, and campaign optimization.


Neuroscience startups help us understand the mental conditions that are affecting humans and are offering solutions that help with detection and treatment. As the benefits of neuroscience are understood, neuroscience startups are working hard to find solutions that would bring those benefits to as many people as possible.

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